Disseminated Cryptococcosis with Adrenal and Lung Involvement in an Immunocompetent Patient
Published: April 1, 2015 | DOI: https://doi.org/10.7860/JCDR/2015/.5752
Piyush Ranjan, Manisha Jana, Shanmugam Krishnan, Devajit Nath, Rita Sood
1. Assistant Professor, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India.
2. Assistant Professor, Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
3. Junior Resident, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India.
4. Senior Resident, Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
5. Professor, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India.
Correspondence
Dr. Rita Sood,
Professor, Department of Medicine, All India Institute of Medical Sciences, New Delhi -110029, India.
E-mail: profritasood@gmail.com
Disseminated cryptococcosis usually occurs in immunocompromised patients. Occasionally, it affects immunocompetent persons and mimics tuberculosis in clinical presentation and radiological findings. Usually, it affects lungs and central nervous system. Rarely, it may affect adrenal glands. We present a case of 65-year-old gentleman with prolonged pyrexia. Computed Tomography (CT) scan of chest and abdomen showed miliary pattern in the chest with bilateral adrenal masses. On the basis of clinical and radiological findings, the case was initially diagnosed as disseminated tuberculosis and anti tubercular treatment was started. Subsequently, on histopathological examination, the diagnosis was confirmed as disseminated cryptococcosis. Even in a country with high prevalence of tuberculosis, other causes of miliary mottling should be considered and histopathological examination should be sought.
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